Lucio Cocco Selected Research

Iron

11/2020	Phospholipase C beta1 (PI-PLCbeta1)/Cyclin D3/protein kinase C (PKC) alpha signaling modulation during iron-induced oxidative stress in myelodysplastic syndromes (MDS).
3/2016	Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy.

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Lucio Cocco Research Topics

Disease

57	Neoplasms (Cancer) 04/2024 - 01/2002
14	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2024 - 05/2007
11	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 09/2015
9	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2023 - 01/2005
9	Leukemia 01/2023 - 02/2005
9	Acute Erythroblastic Leukemia (Erythroleukemia) 09/2017 - 05/2002
8	Breast Neoplasms (Breast Cancer) 01/2021 - 12/2004
5	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 11/2016
4	Neoplasm Metastasis (Metastasis) 01/2022 - 07/2014
4	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 01/2016
3	Glioma (Gliomas) 03/2022 - 03/2007
3	Brain Diseases (Brain Disorder) 02/2022 - 01/2016
3	Myotonic Dystrophy (Dystrophia Myotonica) 01/2017 - 07/2012
3	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 08/2014 - 09/2008
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 03/2011 - 08/2008
2	Inflammation (Inflammations) 04/2024 - 01/2022
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 01/2021
2	Adenocarcinoma 01/2022 - 01/2020
2	Hypoxia (Hypoxemia) 01/2021 - 09/2010
2	Infections 01/2020 - 12/2017
2	Disease Progression 01/2020 - 02/2016
2	Osteosarcoma (Osteogenic Sarcoma) 01/2019 - 01/2006
2	Type 2 Diabetes Mellitus (MODY) 05/2014 - 01/2012
2	Acute Promyelocytic Leukemia 05/2014 - 02/2010
2	Carcinogenesis 12/2012 - 08/2006
2	Astrocytoma (Pilocytic Astrocytoma) 07/2010 - 03/2007
1	Liver Diseases (Liver Disease) 04/2024
1	Hepatocellular Carcinoma (Hepatoma) 04/2024
1	Non-alcoholic Fatty Liver Disease 04/2024
1	Glioblastoma (Glioblastoma Multiforme) 03/2022
1	Laminopathies 02/2022
1	Arteriovenous Fistula 01/2022
1	COVID-19 01/2020

Drug/Important Bio-Agent (IBA)

12	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2024 - 10/2005
9	Type C PhospholipasesIBA 01/2023 - 05/2002
8	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2006
7	Phospholipase C betaIBA 01/2023 - 05/2002
7	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 03/2011
7	Phosphotransferases (Kinase)IBA 07/2020 - 09/2008
6	BerberineIBA 04/2024 - 12/2017
6	EnzymesIBA 01/2022 - 07/2010
6	IsoenzymesIBA 12/2021 - 01/2002
6	Glycogen Synthase Kinase 3IBA 01/2021 - 10/2009
6	Protein Isoforms (Isoforms)IBA 07/2020 - 03/2007
5	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2020 - 01/2006
5	Cyclin D3IBA 11/2020 - 11/2006
4	CytokinesIBA 01/2024 - 12/2004
4	Azacitidine (5 Azacytidine)FDA Link 01/2023 - 06/2013
4	MicroRNAs (MicroRNA)IBA 01/2023 - 09/2015
4	Lamin Type B (Lamin B)IBA 02/2022 - 03/2009
3	Mechanistic Target of Rapamycin Complex 1IBA 01/2022 - 07/2014
3	Protein Kinase CIBA 11/2020 - 03/2009
3	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 01/2006
3	NF-kappa B (NF-kB)IBA 01/2016 - 02/2005
3	ErbB Receptors (EGF Receptor)IBA 01/2016 - 09/2015
3	Hormones (Hormone)IBA 01/2016 - 09/2011
3	ChromatinIBA 08/2014 - 10/2005
3	TNF-Related Apoptosis-Inducing LigandIBA 02/2011 - 01/2006
3	LigandsIBA 11/2008 - 12/2005
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2008 - 12/2004
2	Tumor Suppressor Protein p53IBA 01/2022 - 01/2022
2	nutlin 3IBA 01/2022 - 01/2019
2	epidermal growth factor receptor VIIIIBA 12/2020 - 01/2016
2	IronIBA 11/2020 - 03/2016
2	phosphatidylinositol 3,4,5-triphosphateIBA 04/2020 - 08/2006
2	Estrogen ReceptorsIBA 01/2020 - 11/2016
2	Metformin (Glucophage)FDA LinkGeneric 01/2018 - 09/2015
2	Tamoxifen FDA LinkGeneric 01/2018 - 09/2011
2	ResveratrolIBA 01/2018 - 12/2017
2	Fluorouracil (Carac)FDA LinkGeneric 01/2018 - 01/2018
2	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 01/2016
2	Gemcitabine FDA Link 01/2018 - 01/2018
2	CurcuminIBA 01/2018 - 12/2017
2	beta CateninIBA 02/2017 - 05/2014
2	MTOR InhibitorsIBA 11/2016 - 10/2012
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 05/2014 - 02/2010
2	AntibodiesIBA 02/2011 - 03/2007
2	Small Interfering RNA (siRNA)IBA 09/2010 - 06/2005
2	LipidsIBA 09/2009 - 10/2002
2	AntigensIBA 08/2008 - 12/2004
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 06/2006 - 12/2004
1	Lenalidomide (CC 5013)FDA Link 01/2023
1	LaminsIBA 02/2022
1	eprenetapoptIBA 01/2022
1	HematinicsIBA 01/2021
1	roxadustatIBA 01/2021
1	Phosphatidylinositol PhosphatesIBA 01/2021
1	Daunorubicin (Cerubidine)FDA LinkGeneric 12/2020
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 07/2020
1	DiglyceridesIBA 07/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 04/2020
1	Phosphatidylinositol 4,5-Diphosphate (Phosphatidylinositol 4,5 Diphosphate)IBA 04/2020
1	Trace Elements (Biometals)IBA 01/2020
1	VitaminsIBA 01/2020

Therapy/Procedure

39	Therapeutics 04/2024 - 01/2006
7	Drug Therapy (Chemotherapy) 04/2024 - 01/2006
2	Traditional Medicine (Folk Remedies) 04/2024 - 01/2017
2	Aftercare (After-Treatment) 01/2022 - 07/2010
2	Radiotherapy 01/2019 - 11/2011
1	TP protocol 12/2020